SCHEMBL29958896

SCHEMBL29958896

CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2ccnc2C(C)(C)C)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 17/20 0.61
AGTR1 P30556 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25576364 1.00 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL29958619 0.93 AGTR2 (0.53) AGTR2AGTR1
SCHEMBL29958648 0.93 AGTR2 (0.51) AGTR2AGTR1
SCHEMBL29958707 0.91 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL29958531 0.91 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL29958610 0.91 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL23831165 0.91 AGTR2 (0.71) AGTR2AGTR1
SCHEMBL29958721 0.91 AGTR2 (0.56) AGTR2AGTR1
SCHEMBL25576366 0.91 AGTR2 (0.56) AGTR2AGTR1
SCHEMBL23831132 0.88 AGTR2 (0.47) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159467-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-05-25 US claimed
EP-4121165-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-01-25 EP claimed
US-20240182461-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2024-06-06 US disclosed
EP-4313953-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP disclosed
US-20230159467-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-05-25 US disclosed
EP-4121165-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-01-25 EP disclosed
CN-115605265-A Novel compounds for the treatment and/or prevention of diseases, disorders or conditions associated with angiotensin ii 维科尔药物公司(SE) 2023-01-13 CN disclosed
WO-2022200785-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182461-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS AGTR1, AGTR2, MSR1 AGTR2 2/4885AGTR1 1/4885
US-20230159467-A1 NOVEL COMPOUNDS USEFUL IN THE TREATMENT AND/OR PREVENTION OF A DISEASE, DISORDER OR CONDITION ASSOCIATED WITH ANGIOTENSIN II AGTR2, AGTR1, AGT AGTR2 1/4885AGTR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.