Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579067 | 1.00 | CTSS (0.36) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23579068 | 1.00 | CTSS (0.36) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL24969956 | 1.00 | CTSS (0.36) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23579069 | 1.00 | CTSS (0.36) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23579286 | 0.84 | KDM1A (0.38) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23593521 | 0.84 | KDM1A (0.38) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23593602 | 0.84 | KDM1A (0.38) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23578759 | 0.84 | KDM1A (0.38) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23593536 | 0.84 | KDM1A (0.38) | CTSSKDM4EHPGDCD38ALDH1A1 | |
| SCHEMBL23593515 | 0.84 | ALDH1A1 (0.43) | KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135642-B | Inhibitors of EGFR mutant forms | 缆图药品公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4081515-A1 | INHIBITORS OF MUTANT FORMS OF EGFR | Blueprint Medicines Corporation (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-115135642-A | Inhibitors of mutant forms of EGFR | 缆图药品公司 | 2022-09-30 | — | — | CN | disclosed |