Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553613 | 1.00 | PDE2A (0.59) | PDE2AMDM2KCNH2MEN1KMT2A | |
| SCHEMBL23212834 | 1.00 | PDE2A (0.59) | PDE2AMDM2KCNH2MEN1KMT2A | |
| SCHEMBL17215540 | 1.00 | PDE2A (0.59) | PDE2AMDM2KCNH2MEN1KMT2A | |
| SCHEMBL30142930 | 0.85 | PDE2A (0.47) | PDE2AKCNH2MEN1KMT2ACES2 | |
| SCHEMBL17216071 | 0.85 | PDE2A (0.47) | PDE2AKCNH2MEN1KMT2ACES2 | |
| SCHEMBL23489650 | 0.85 | PDE2A (0.47) | PDE2AKCNH2MEN1KMT2ACES2 | |
| SCHEMBL2588946 | 0.85 | PDE2A (0.47) | PDE2AKCNH2MEN1KMT2ACES2 | |
| SCHEMBL420958 | 0.83 | LMNA (0.42) | PDE2AMDM2KCNH2LMNATP53 | |
| SCHEMBL17061753 | 0.81 | LMNA (0.41) | PDE2AMDM2KCNH2LMNATP53 | |
| SCHEMBL17553268 | 0.79 | LMNA (0.39) | PDE2AMDM2KCNH2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823112-A | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115135645-B | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115135645-A | ATF6 modulators and uses thereof | 普拉西斯生物技术有限责任公司 | 2022-09-30 | — | — | CN | disclosed |