Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338819 | 0.81 | ATM (0.44) | ATM | |
| SCHEMBL17974163 | 0.76 | ESR1 (0.40) | SLC6A3SLC6A4 | |
| SCHEMBL30901243 | 0.72 | MAOA (0.39) | ATM | |
| SCHEMBL29586848 | 0.71 | KMT2A (0.41) | ALDH1A1ATMCYP3A4TSHRHSD17B10 | |
| SCHEMBL29586933 | 0.71 | KMT2A (0.41) | ALDH1A1ATMCYP3A4TSHRHSD17B10 | |
| SCHEMBL24496707 | 0.71 | KMT2A (0.41) | ALDH1A1ATMCYP3A4TSHRHSD17B10 | |
| SCHEMBL6327261 | 0.71 | KMT2A (0.41) | ALDH1A1ATMCYP3A4TSHRHSD17B10 | |
| SCHEMBL28963664 | 0.70 | SLC6A3 (0.36) | SLC6A3SLC6A4ALDH1A1ATMCYP3A4 | |
| SCHEMBL29587118 | 0.70 | KMT2A (0.40) | ALDH1A1ATMTSHRHSD17B10GAA | |
| SCHEMBL16751353 | 0.69 | HTT (0.40) | ALDH1A1CYP3A4MAPK1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476648-B | Sevelamer antibody-drug conjugates and methods of use | 豪夫迈·罗氏有限公司 | 2022-09-13 | — | — | CN | disclosed |