Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21829027 | 1.00 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL21828975 | 0.82 | MAPT (0.70) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21829001 | 0.82 | MAPT (0.70) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21828973 | 0.82 | MAPT (0.70) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21828987 | 0.82 | MAPT (0.69) | MAPTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL21829002 | 0.81 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21829009 | 0.81 | MAPT (0.68) | MAPTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL21829008 | 0.80 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21829017 | 0.80 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21829028 | 0.80 | PTGS2 (0.77) | MAPTKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240423927-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | INSTITUT CURIE (FR) | 2024-12-26 | — | — | US | claimed |
| EP-4346894-A1 | ADJUVANTS | GlaxoSmithKline Biologicals S.A. (BE) | 2024-04-10 | — | — | EP | claimed |
| EP-4326769-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | Institut Curie (FR) | 2024-02-28 | — | — | EP | claimed |
| WO-2022248353-A1 | ADJUVANTS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-12-01 | — | — | WO | claimed |
| WO-2022223619-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | INSTITUT CURIE (FR) | 2022-10-27 | — | — | WO | claimed |
| WO-2025080869-A1 | PANCREATIC CANCER IMMUNOTHERAPY USING CATIONIC LIPID AND POLYMER NANOCARRIERS FOR CO-DELIVERY OF KRAS NEOANTIGENS AND STING AND/OR OTHER IMMUNOMODULATORS TO BOOST THE CANCER IMMUNITY CYCLE AND TREAT LIVER METASTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-04-17 | — | — | WO | disclosed |
| US-20240423927-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | INSTITUT CURIE (FR) | 2024-12-26 | — | — | US | disclosed |
| EP-4346894-A1 | ADJUVANTS | GlaxoSmithKline Biologicals S.A. (BE) | 2024-04-10 | — | — | EP | disclosed |
| EP-4326769-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | Institut Curie (FR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2023020992-A1 | NOVEL METHODS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023020994-A1 | NOVEL METHODS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023020993-A1 | NOVEL METHODS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2022248353-A1 | ADJUVANTS | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-12-01 | — | — | WO | disclosed |
| WO-2022223619-A1 | COMPOSITIONS AND METHODS FOR USE IN IMMUNOTHERAPY | INSTITUT CURIE (FR) | 2022-10-27 | — | — | WO | disclosed |