Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 14/20 | 0.68 |
| ▸ | NPC1 | O15118 | 12/20 | 0.68 |
| ▸ | PKM | P14618 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24004496 | 0.92 | RAB9A (0.68) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL21829029 | 0.90 | RAB9A (0.64) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL17131817 | 0.81 | PTGS2 (0.86) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL11830460 | 0.81 | NPC1 (0.85) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL21829027 | 0.80 | MAPT (1.00) | PTGS2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL29959525 | 0.80 | MAPT (1.00) | PTGS2RAB9ANPC1ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL7335932 | 0.80 | PLAU (0.57) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL28401891 | 0.79 | PTGS2 (0.77) | PTGS2RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL21914836 | 0.78 | NPC1 (0.80) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL12368146 | 0.78 | RAB9A (1.00) | PTGS2RAB9ANPC1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE | 2021-11-11 | — | — | US | disclosed |
| WO-2020072492-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | BARUCH S. BLUMBERG INSTITUTE (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347752-A1 | BENZAMIDE DERIVATIVES AS CGAS-STING PATHWAY AGONISTS | STING1, CGAS, MAVS | PTGS2 699/4885RAB9A 1646/4885NPC1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.