Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970204 | 0.80 | MAOA (0.64) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL11728246 | 0.79 | MAOA (0.62) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL6129307 | 0.79 | MAOA (0.62) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL1979794 | 0.79 | MAOA (0.62) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL521775 | 0.78 | MAOA (1.00) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL29419966 | 0.78 | MAOA (1.00) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL28681589 | 0.76 | MAOA (0.95) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL22868019 | 0.75 | MAOA (0.56) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL29960202 | 0.75 | MAOA (0.39) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL18287902 | 0.72 | MAOA (0.58) | MAOAMAOBATMHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |