SCHEMBL7970204

SCHEMBL7970204

Oc1cccc2c1C(O)c1ccccc1O2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.64
MAOB P27338 1/20 0.64
GUSB P08236 1/20 0.44
ATM Q13315 1/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
GAA P10253 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
CYP2C9 P11712 1/20 0.39
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979794 0.80 MAOA (0.62) MAOAMAOBGUSBATMMEN1
SCHEMBL29959896 0.80 MAOA (0.62) MAOAMAOBGUSBATMMEN1
SCHEMBL11728246 0.80 MAOA (0.62) MAOAMAOBGUSBATMMEN1
SCHEMBL6129307 0.80 MAOA (0.62) MAOAMAOBGUSBATMMEN1
SCHEMBL29419966 0.80 MAOA (1.00) MAOAMAOBATMMEN1KMT2A
SCHEMBL521775 0.80 MAOA (1.00) MAOAMAOBATMMEN1KMT2A
SCHEMBL28681589 0.78 MAOA (0.95) MAOAMAOBATMMEN1KMT2A
SCHEMBL5475173 0.77 CYP2C9 (0.46) MAOAMAOBATMMEN1KMT2A
SCHEMBL22868019 0.76 MAOA (0.56) MAOAMAOBATMMEN1KMT2A
SCHEMBL2721424 0.76 MAOA (0.74) MAOAMAOBGUSBATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103954722-A Detection method aiming at trace urea in white spirit UNIV JIANGNAN 2014-07-30 CN disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed
EP-0357350-B1 Novel xanthene dyes BECTON DICKINSON CO (US) 1994-01-19 EP disclosed
US-5066580-A Fluorescent dyes coupled to antibodies useful in cell detection, blood, urine, bone marrow analysis BECTON DICKINSON AND COMPANY (US) 1991-11-19 US disclosed
EP-0110682-B1 ACTIVATED ARYL CAPPED FLUORESCENT COMPOUNDS, AND ASSAY METHODS AND SYSTEMS USING THEM AS FLUOROGENIC PRECURSORS SYVA COMPANY (US) 1991-08-21 EP disclosed
US-4933471-A FLUORESCENT, USED IN CELL ANALYSIS, CARBOXY OR SULFO SUBSTITUTED BECTON, DICKINSON AND COMPANY (US) 1990-06-12 US disclosed
EP-0357350-A2 Novel xanthene dyes Becton, Dickinson and Company (US) 1990-03-07 EP disclosed