Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959780 | 1.00 | PDE4B (0.53) | PDE4BMEN1KMT2AGPR119JAK2 | |
| SCHEMBL10841569 | 0.89 | PDE4B (0.50) | PDE4BMEN1KMT2AKDM4EPDE4A | |
| SCHEMBL29960667 | 0.87 | TERT (0.48) | PDE4BGPR119JAK2JAK1KDM4E | |
| SCHEMBL23982323 | 0.83 | PDE4B (0.52) | PDE4BMEN1KMT2AGPR119JAK2 | |
| SCHEMBL16141295 | 0.83 | TACR1 (0.54) | PDE4BGPR119JAK2JAK1KDM4E | |
| SCHEMBL4709680 | 0.83 | TACR1 (0.54) | PDE4BGPR119JAK2JAK1KDM4E | |
| SCHEMBL4710562 | 0.83 | TACR1 (0.54) | PDE4BGPR119JAK2JAK1KDM4E | |
| SCHEMBL16108769 | 0.83 | TACR1 (0.54) | PDE4BGPR119JAK2JAK1KDM4E | |
| SCHEMBL25044033 | 0.82 | MEN1 (0.59) | PDE4BMEN1KMT2AGPR119ALDH1A1 | |
| SCHEMBL29960410 | 0.81 | PDE4B (0.47) | PDE4BMEN1KMT2AGPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |