Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959780 | 0.87 | PDE4B (0.53) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL29960229 | 0.87 | PDE4B (0.53) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL3062560 | 0.85 | GPR119 (0.48) | TERTGPR119JAK2JAK1KDM4E | |
| SCHEMBL16108769 | 0.85 | TACR1 (0.54) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL16141295 | 0.85 | TACR1 (0.54) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL4709680 | 0.85 | TACR1 (0.54) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL4710562 | 0.85 | TACR1 (0.54) | GPR119PDE4BJAK2JAK1KDM4E | |
| SCHEMBL16108051 | 0.80 | DPP4 (0.49) | GPR119PDE4BKDM4ETACR1THRB | |
| SCHEMBL14934715 | 0.80 | DPP4 (0.49) | GPR119PDE4BKDM4ETACR1THRB | |
| SCHEMBL16141406 | 0.80 | DPP4 (0.49) | GPR119PDE4BKDM4ETACR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |