Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528967 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15486212 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL7677183 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRMAPTL3MBTL1 | |
| SCHEMBL27518977 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRMAPTCDK5 | |
| SCHEMBL9715487 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP1A2TSHRMAPTKMT2A | |
| SCHEMBL17111504 | 0.77 | KDM4E (0.38) | ALDH1A1CYP1A2MAPTL3MBTL1KMT2A | |
| SCHEMBL8552393 | 0.76 | MAPT (0.46) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL10091749 | 0.76 | ALDH1A1 (0.77) | ALDH1A1CYP1A2TSHRMAPTL3MBTL1 | |
| SCHEMBL27987013 | 0.76 | ALDH1A1 (0.63) | ALDH1A1CYP1A2TSHRMAPTL3MBTL1 | |
| SCHEMBL988882 | 0.76 | TSHR (0.48) | ALDH1A1TSHRKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |