Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853528 | 0.82 | MAPT (0.43) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL20718828 | 0.82 | MAPT (0.43) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL20718842 | 0.81 | SMN1; SMN2 (0.39) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL9715487 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL1641895 | 0.78 | MAPT (0.47) | MAPTLMNAALDH1A1KMT2AGAA | |
| SCHEMBL15486212 | 0.76 | MAPT (0.49) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL29528967 | 0.76 | MAPT (0.49) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL29960754 | 0.76 | ALDH1A1 (0.49) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL8552390 | 0.74 | ALDH1A1 (0.42) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL11819183 | 0.73 | SMN1; SMN2 (0.42) | MAPTALDH1A1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |