SCHEMBL29960801

SCHEMBL29960801

O=C1Nc2cscc2[C@@H]2CN(Cc3ccccc3)C[C@@H]12

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.43
DRD3 P35462 2/20 0.43
RORC P51449 2/20 0.42
FUCA1 P04066 2/20 0.39
DPP4 P27487 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR5 Q9H228 1/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
TBXA2R P21731 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11031885 0.82 FUCA1 (0.51) DRD2DRD3RORCFUCA1S1PR1
SCHEMBL1505186 0.82 FUCA1 (0.51) DRD2DRD3RORCFUCA1S1PR1
SCHEMBL583636 0.82 FUCA1 (0.51) DRD2DRD3RORCFUCA1S1PR1
SCHEMBL29960698 0.77 RORC (0.42) DRD2DRD3RORCFUCA1S1PR1
SCHEMBL29961188 0.77 FUCA1 (0.42) DRD2DRD3RORCFUCA1DPP4
SCHEMBL29960624 0.77 FUCA1 (0.42) DRD2DRD3RORCFUCA1DPP4
SCHEMBL24535980 0.76 FUCA1 (0.51) DRD2DRD3RORCFUCA1S1PR1
SCHEMBL31503775 0.73 CCR1 (0.43) DRD2DRD3DPP4S1PR1S1PR5
SCHEMBL1803867 0.71 SIGMAR1 (0.45) DRD2DRD3RORCFUCA1DPP4
SCHEMBL1803869 0.71 SIGMAR1 (0.45) DRD2DRD3RORCFUCA1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed