SCHEMBL29960811

SCHEMBL29960811

CC1(C)COC2C(=O)NCCc3cccc1c32

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.35
PARP10 Q53GL7 2/20 0.33
PDPK1 O15530 1/20 0.33
PARP11 Q9NR21 1/20 0.33
HTR2C P28335 1/20 0.31
SRD5A1 P18405 1/20 0.30
MAP2K1 Q02750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29960741 0.72 HTR2C (0.43) HTR2C
SCHEMBL29960392 0.59 PARP10 (0.36) PARP1PARP10PARP11HTR2C
SCHEMBL2275422 0.58 HTR2A (0.50) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL17457429 0.56 GID4 (0.44) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL12714991 0.56 PARP10 (0.54) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL7772712 0.55 PRCP (0.42) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL8367481 0.55 HTR2A (0.43) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL14178994 0.55 PDPK1 (0.45) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL4127623 0.55 ANPEP (0.50) PARP1PARP10PDPK1PARP11HTR2C
SCHEMBL4117416 0.55 ANPEP (0.50) PARP1PARP10PDPK1PARP11HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed