SCHEMBL29960949

SCHEMBL29960949

N#CC1=CCOc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
CYP19A1 P11511 5/20 0.35
MAOB P27338 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
KDM4E B2RXH2 5/20 0.33
GLA P06280 4/20 0.33
PIM1 P11309 3/20 0.33
GAA P10253 2/20 0.33
ATM Q13315 2/20 0.33
POLB P06746 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
KMT2A Q03164 2/20 0.32
RUNX1 Q01196 1/20 0.32
CBFB Q13951 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7407809 1.00 PKM (0.38) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL2004582 0.81 TSHR (0.42) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL9432216 0.75 FABP6 (0.40) CYP19A1KDM4EGAAALDH1A1MAPT
SCHEMBL8309740 0.74 PKM (0.36) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL28569718 0.73 PKM (0.35) PKMTSHRABCG2ITGB2ICAM1
SCHEMBL5270297 0.70 OPRD1 (0.35) PKMTSHRCYP19A1KMT2AALDH1A1
SCHEMBL294469 0.69 TSHR (0.42) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL276292 0.69 PKM (0.47) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL5541737 0.69 PKM (0.42) PKMTSHRCYP19A1MAOBABCG2
SCHEMBL294470 0.69 PKM (0.42) PKMTSHRCYP19A1MAOBABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed