SCHEMBL29960964

SCHEMBL29960964

O=C(Nc1ccccc1Cl)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.74
RAB9A P51151 4/20 0.74
L3MBTL1 Q9Y468 2/20 0.70
ALDH1A1 P00352 2/20 0.70
GLA P06280 1/20 0.70
ATM Q13315 1/20 0.70
APOBEC3A P31941 1/20 0.68
CTDSP1 Q9GZU7 1/20 0.68
APOBEC3G Q9HC16 1/20 0.68
HPGD P15428 3/20 0.67
CYP1A2 P05177 2/20 0.67
CYP2C19 P33261 1/20 0.67
MAPT P10636 3/20 0.63
HDAC1 Q13547 2/20 0.63
HDAC8 Q9BY41 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
MEN1 O00255 1/20 0.63
LMNA P02545 1/20 0.63
KMT2A Q03164 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794850 1.00 NPC1 (0.74) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL13726997 0.91 CYP1A2 (0.72) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL16583878 0.91 NPC1 (0.73) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL14252928 0.89 MEN1 (0.79) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL29083336 0.87 NPC1 (0.62) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL28577755 0.87 NPC1 (0.73) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL9621459 0.87 MEN1 (0.82) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL3785470 0.85 LMNA (0.66) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL25229349 0.85 NPC1 (0.71) NPC1RAB9AL3MBTL1ALDH1A1GLA
SCHEMBL13881198 0.85 RAB9A (1.00) NPC1RAB9AL3MBTL1ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369038-B Method for synthesizing amide compound by photocatalysis 苏州大学张家港工业技术研究院 2023-06-23 CN disclosed
CN-115043750-A Method for preparing formamide under low pressure 中国科学院山西煤炭化学研究所 2022-09-13 CN disclosed