Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289013 | 0.95 | MAPT (0.47) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3765673 | 0.94 | MAPT (0.42) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3707169 | 0.94 | MAPT (0.48) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3221010 | 0.90 | MAPT (0.39) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL297406 | 0.89 | MAPT (0.51) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3215108 | 0.89 | MAPT (0.44) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3201501 | 0.88 | LMNA (0.41) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3702064 | 0.87 | MAPT (0.43) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3205415 | 0.85 | MAPT (0.41) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL3695537 | 0.85 | KCNQ3 (0.35) | MAPTKMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242998-B | Use of 4-cyano-3-benzoylamino-N-phenyl-benzamides in pesticides | 先正达参股股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-2427427-B1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127926-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010127926-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | NISCH, AADAC, ACHE | MAPT 3060/4885KMT2A 901/4885MEN1 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.