Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797818 | 0.87 | NOS2 (0.38) | NOS2NOS3NOS1CYP3A4CYP1A2 | |
| SCHEMBL293171 | 0.86 | NOS2 (0.40) | NOS2CYP2D6HRH1CYP3A4CYP1A2 | |
| SCHEMBL12301340 | 0.85 | KCNH2 (0.44) | NOS2CYP2D6HRH1HSD17B10KDM4E | |
| SCHEMBL22341560 | 0.83 | KCNH2 (0.47) | CYP3A4HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL19309229 | 0.83 | KCNH2 (0.47) | CYP3A4HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL294175 | 0.81 | KDM4E (0.32) | NOS2NOS3NOS1CYP3A4TSHR | |
| SCHEMBL97386 | 0.81 | CYP2D6 (0.35) | CYP2D6HRH1CYP3A4CYP1A2CLK4 | |
| SCHEMBL110053 | 0.80 | — | — | |
| SCHEMBL2339199 | 0.79 | HRH1 (0.42) | CYP2D6HRH1CYP3A4CYP1A2CLK4 | |
| SCHEMBL22877018 | 0.79 | CYP2D6 (0.34) | CYP2D6HRH1CYP3A4CYP1A2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490938-A | Bacillus bailii BL-LM and application thereof in preparation of special-flavor white spirit Daqu | 江西农业大学 | 2025-02-21 | — | — | CN | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| US-20250214975-A1 | PEPTIDYL FLAVOR MODIFIERS | OHIO STATE INNOVATION FOUNDATION | 2025-07-03 | — | — | US | disclosed |
| CN-119490938-A | Bacillus bailii BL-LM and application thereof in preparation of special-flavor white spirit Daqu | 江西农业大学 | 2025-02-21 | — | — | CN | disclosed |
| US-12213502-B2 | Method of enhancing flavor qualities of coffee using novel small molecules | OHIO STATE INNOVATION FOUNDATION (US) | 2025-02-04 | — | — | US | disclosed |
| US-20240090549-A1 | NOVEL SMALL MOLECULES THAT ENHANCE FLAVOR QUALITIES OF COFFEE AND RELATED BEVERAGES | OHIO STATE INNOVATION FOUNDATION | 2024-03-21 | — | — | US | disclosed |
| US-11891364-B2 | Methods of selectively forming substituted pyrazines | R.J. REYNOLDS TOBACCO COMPANY (US) | 2024-02-06 | — | — | US | disclosed |
| CN-117486811-A | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11856975-B2 | Method of enhancing flavor qualities of coffee | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-02 | — | — | US | disclosed |
| CN-110637012-B | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023225277-A1 | PEPTIDYL FLAVOR MODIFIERS | OHIO STATE INNOVATION FOUNDATION (US) | 2023-11-23 | — | — | WO | disclosed |
| US-4847355-A | Thermosettable prepolymer prepared from heterocyclic material having alkyl substituents, mono- or dianhydride, ethylenically unsaturated material and a hydroxide, carbonate of bicarbonate of a metal of groups I-A or II-A | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4812531-A | Thermosettable polymers or prepolymers prepared from heterocyclic materials having alkyl substituents, mono- or dianhydrides, ethylenically unsaturated materials and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A | THE DOW CHEMICAL COMPANY (US) | 1989-03-14 | — | — | US | disclosed |
| US-4752636-A | Thermosettable polymer or prepolymer prepared from heterocyclic materials containing nitrogen atoms, carboxylic acid mono- or dianhydrides and a polymerizable material with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1988-06-21 | — | — | US | disclosed |
| US-4668766-A | Preparation of thermosettable polymer or prepolymer from heterocyclic material containing nitrogen atoms, carboxylic acid mono- or dianhydride and a polymerizable material with ethylenically unsaturated group | THE DOW CHEMICAL COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4654414-A | Thermosettable polymer or prepolymer prepared from heterocyclic material having alkyl substituent, mono- or dianhydride, ethylenically unsaturated material and a hydroxide, carbonate or bicarbonate of a metal of groups I-A or II-A | THE DOW CHEMICAL COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4613663-A | Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes | THE DOW CHEMICAL COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0002938-B1 | NOVEL HETEROCYCLIC CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4289766-A | Heterocyclic carbothioamides | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214975-A1 | PEPTIDYL FLAVOR MODIFIERS | TAS2R30, TAS2R40, TAS2R50 | NOS2 2485/4885NOS3 1406/4885NOS1 1967/4885 |
| US-11891364-B2 | Methods of selectively forming substituted pyrazines | KHK, HK2, HK1 | NOS2 1932/4885NOS3 2076/4885NOS1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.