Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746239 | 0.88 | MME (0.42) | KIF11ALDH1A1LMNAMMP9MMP1 | |
| SCHEMBL6746235 | 0.88 | MME (0.42) | KIF11ALDH1A1LMNAMMP9MMP1 | |
| SCHEMBL9510086 | 0.87 | MME (0.41) | KIF11ALDH1A1LMNAMMP9MMP1 | |
| SCHEMBL9510102 | 0.87 | MME (0.41) | KIF11LMNAMMP9MMP1MMP2 | |
| SCHEMBL29964989 | 0.84 | KIF11 (0.50) | KIF11NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL5413934 | 0.81 | KMT2A (0.43) | KIF11KMT2ACES1PTGS2L3MBTL1 | |
| SCHEMBL1109144 | 0.81 | KMT2A (0.43) | KIF11KMT2ACES1PTGS2L3MBTL1 | |
| SCHEMBL12379297 | 0.81 | KMT2A (0.43) | KIF11KMT2ACES1PTGS2L3MBTL1 | |
| SCHEMBL1105488 | 0.81 | KMT2A (0.43) | KIF11KMT2ACES1PTGS2L3MBTL1 | |
| SCHEMBL5413928 | 0.81 | KMT2A (0.43) | KIF11KMT2ACES1PTGS2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | claimed |
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |