Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17542012 | 0.88 | KIF11 (0.48) | KIF11SMN1; SMN2NPC1RAB9ACES2 | |
| SCHEMBL17542010 | 0.88 | KIF11 (0.48) | KIF11SMN1; SMN2NPC1RAB9ACES2 | |
| SCHEMBL10901575 | 0.87 | KCNN4 (0.45) | KIF11SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL11128706 | 0.87 | KCNN4 (0.45) | KIF11SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL9037241 | 0.87 | KCNN4 (0.45) | KIF11SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL29964869 | 0.84 | KIF11 (0.47) | KIF11SMN1; SMN2NPC1RAB9ACES2 | |
| SCHEMBL29964838 | 0.83 | KIF11 (0.46) | KIF11SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19347961 | 0.83 | ACP3 (0.43) | KIF11SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21947369 | 0.81 | KIF11 (0.45) | KIF11SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19347962 | 0.81 | KIF11 (0.45) | KIF11SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |