Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647476 | 0.86 | DPP4 (0.45) | MAOBDPP4FAPDPP8DPP9 | |
| SCHEMBL21144842 | 0.84 | DPP4 (0.48) | MAOBDPP4FAPDPP8DPP9 | |
| SCHEMBL21144845 | 0.84 | DPP4 (0.48) | MAOBDPP4FAPDPP8DPP9 | |
| SCHEMBL23270320 | 0.84 | DPP4 (0.48) | MAOBDPP4FAPDPP8DPP9 | |
| SCHEMBL30440024 | 0.83 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL11357126 | 0.83 | ALPI (0.56) | MAOBSLC7A5CTSCALPIPKM | |
| SCHEMBL29964940 | 0.82 | TDP1 (0.46) | MAOBDPP4FAPDPP8DPP9 | |
| SCHEMBL43593 | 0.78 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL43594 | 0.78 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL838534 | 0.78 | SLC7A5 (0.62) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |