Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440024 | 0.87 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL11357126 | 0.86 | ALPI (0.56) | SLC7A5MAOBALPIPKMPTGS1 | |
| SCHEMBL18171811 | 0.83 | TDP1 (0.44) | TDP1TPH1SLC7A5MAOBDPP4 | |
| SCHEMBL18171813 | 0.83 | TDP1 (0.44) | TDP1TPH1SLC7A5MAOBDPP4 | |
| SCHEMBL29965012 | 0.82 | MAOB (0.52) | TPH1SLC7A5MAOBDPP4FAP | |
| SCHEMBL24633773 | 0.81 | NR1D1 (0.42) | TDP1TPH1SLC7A5MAOBDPP4 | |
| SCHEMBL29965205 | 0.79 | PNMT (0.49) | TDP1SLC7A5MAOBDPP4DPP7 | |
| SCHEMBL25083941 | 0.76 | SLC7A5 (0.56) | SLC7A5 | |
| SCHEMBL44071 | 0.76 | SLC7A5 (0.69) | TDP1TPH1SLC7A5ALPIPKM | |
| SCHEMBL23320242 | 0.76 | SLC7A5 (0.69) | TDP1TPH1SLC7A5ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |