Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458852 | 1.00 | CYP2A6 (0.45) | CYP2A6DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL23482386 | 0.86 | CYP2A6 (0.45) | CYP2A6DAO | |
| SCHEMBL23482394 | 0.75 | CYP2A6 (0.53) | CYP2A6DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL24842310 | 0.75 | CYP2A6 (0.36) | CYP2A6 | |
| SCHEMBL19624951 | 0.73 | TBXAS1 (0.36) | DAOHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4960807 | 0.72 | CYP2A6 (0.49) | CYP2A6DAOHDAC3HDAC6 | |
| SCHEMBL31440929 | 0.71 | AHR (0.42) | CYP2A6 | |
| SCHEMBL29466343 | 0.70 | CYP2A6 (0.58) | CYP2A6DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5361224 | 0.70 | CYP2A6 (0.58) | CYP2A6DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30489877 | 0.69 | HDAC3 (0.35) | CYP2A6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |