Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922284 | 0.84 | PNMT (0.56) | PNMTMAOBMAOAKMOSLC6A2 | |
| SCHEMBL26922280 | 0.84 | PNMT (0.56) | PNMTMAOBMAOAKMOSLC6A2 | |
| SCHEMBL30440024 | 0.80 | SLC7A5 (0.58) | PTGS1SLC7A5SLC6A2 | |
| SCHEMBL11357126 | 0.80 | ALPI (0.56) | MAOBMAOAPTGS1SLC7A5SLC6A2 | |
| Hydrochloric Acid SCHEMBL8148706 | 0.80 | PNMT (0.44) | PNMTMAOBMAOATDP1SLC6A2 | |
| SCHEMBL29964940 | 0.79 | TDP1 (0.46) | MAOBPTGS1SLC7A5TDP1DPP4 | |
| SCHEMBL8153300 | 0.78 | PNMT (0.42) | PNMTMAOBMAOASLC6A2SLC6A4 | |
| SCHEMBL8140617 | 0.78 | MC4R (0.49) | PNMTHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL683674 | 0.78 | PNMT (0.62) | PNMTKMOKIF11KDM4EUSP2 | |
| SCHEMBL21930623 | 0.78 | PNMT (0.62) | PNMTKMOKIF11KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |