Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068475 | 0.86 | ALDH1A1 (0.52) | KMT2AALOX5PTGESALDH1A1GAA | |
| SCHEMBL31365678 | 0.83 | KMT2A (0.75) | PDGFRBPDGFRAKMT2APKMPTGES | |
| SCHEMBL27858102 | 0.83 | KMT2A (0.75) | PDGFRBPDGFRAKMT2APKMPTGES | |
| SCHEMBL17898566 | 0.81 | MAPT (0.53) | PDGFRBPDGFRAKMT2APKMALOX5 | |
| SCHEMBL30128440 | 0.81 | KMT2A (0.58) | PDGFRBPDGFRAKMT2AALDH1A1KDM4E | |
| SCHEMBL27661957 | 0.81 | KMT2A (0.58) | KMT2AALDH1A1MAPTMEN1TDP1 | |
| SCHEMBL27945114 | 0.80 | KMT2A (0.71) | PDGFRBPDGFRAKMT2APKMPTGES | |
| SCHEMBL18325183 | 0.80 | MAPT (0.67) | PDGFRBPDGFRAKMT2APKMALOX5 | |
| SCHEMBL4951809 | 0.80 | KMT2A (0.84) | KMT2APKMALOX5NR1H4ALDH1A1 | |
| SCHEMBL10636579 | 0.80 | KMT2A (0.84) | KMT2APKMALOX5NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151260-A | Fulvestrant prodrugs | 卡希夫生物科学有限公司 | 2022-10-04 | — | — | CN | disclosed |