Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23663122 | 1.00 | TUBB1 (0.48) | TUBB1ERN1ALDH1A1THRBRORC | |
| SCHEMBL6374646 | 0.83 | TUBB1 (0.57) | TUBB1ERN1ALDH1A1THRBRORC | |
| SCHEMBL7039684 | 0.83 | TUBB1 (0.45) | TUBB1ERN1ALDH1A1THRBRORC | |
| SCHEMBL4961567 | 0.82 | TLR9 (0.49) | TUBB1ERN1ALDH1A1THRBRORC | |
| SCHEMBL12312519 | 0.80 | THRB (0.49) | TUBB1THRBRORCTHRAJUN | |
| SCHEMBL23663148 | 0.80 | THRB (0.46) | TUBB1ALDH1A1THRBRORCTHRA | |
| SCHEMBL31287740 | 0.80 | TUBB1 (0.49) | TUBB1ERN1ALDH1A1KDM4ETSHR | |
| SCHEMBL23663331 | 0.78 | THRB (0.41) | THRBRORCTHRA | |
| SCHEMBL23663266 | 0.78 | THRB (0.42) | TUBB1ALDH1A1THRBRORCTHRA | |
| SCHEMBL23663084 | 0.78 | POLB (0.52) | ALDH1A1THRBRORCTHRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244037-B | Substituted triazinones as thyroid hormone receptor agonists | 诚益生物(美国)公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-4090652-A1 | SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS | Eccogene (Shanghai) Co., Ltd. (CN) | 2022-11-23 | — | — | EP | disclosed |
| CN-115244037-A | Substituted triazinones as thyroid hormone receptor agonists | 上海诚益生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |