Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937133 | 1.00 | HTR1F (0.58) | HTR1FKDM4ELMNARXFP1P4HTM | |
| SCHEMBL28937135 | 0.84 | RXFP1 (0.78) | HTR1FKDM4ELMNARXFP1P4HTM | |
| SCHEMBL28937138 | 0.84 | HTR1F (0.58) | HTR1FKDM4ERXFP1NPC1RAB9A | |
| SCHEMBL28937144 | 0.84 | HTR1F (0.60) | HTR1FKDM4ELMNAP4HTMGRM5 | |
| SCHEMBL29965342 | 0.84 | HTR1F (0.60) | HTR1FKDM4ELMNAP4HTMGRM5 | |
| SCHEMBL28795275 | 0.79 | KDM4E (0.55) | KDM4ELMNARXFP1NPC1RAB9A | |
| SCHEMBL211889 | 0.78 | P4HTM (0.59) | KDM4EP4HTM | |
| SCHEMBL28937119 | 0.76 | HTR1F (0.63) | HTR1FKDM4ELMNARXFP1NPC1 | |
| SCHEMBL31474568 | 0.76 | P4HTM (0.57) | KDM4EP4HTM | |
| Hydrochloric Acid SCHEMBL1828697 | 0.76 | P4HTM (0.57) | KDM4EP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |