Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 5/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937144 | 1.00 | HTR1F (0.60) | HTR1FKDM4ELMNAGRM5P4HTM | |
| SCHEMBL28963589 | 0.85 | MAPT (0.61) | HTR1FKDM4EGRM5XIAPBIRC2 | |
| SCHEMBL29965657 | 0.84 | HTR1F (0.58) | HTR1FKDM4ELMNAGRM5P4HTM | |
| SCHEMBL28937133 | 0.84 | HTR1F (0.58) | HTR1FKDM4ELMNAGRM5P4HTM | |
| SCHEMBL28937159 | 0.82 | MEN1 (0.60) | HTR1FKDM4ELMNAGRM5P4HTM | |
| SCHEMBL23528940 | 0.78 | HTR1F (0.73) | HTR1FGRM5 | |
| SCHEMBL28937149 | 0.77 | HTR1F (0.61) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL110129 | 0.77 | P4HTM (0.59) | KDM4ELMNAP4HTMMEN1KMT2A | |
| SCHEMBL30449388 | 0.77 | P4HTM (0.59) | KDM4ELMNAP4HTMMEN1KMT2A | |
| SCHEMBL23733275 | 0.77 | MEN1 (0.62) | HTR1FKDM4ELMNAGRM5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |