⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564844 | 0.82 | FAAH (0.46) | — | |
| SCHEMBL253070 | 0.81 | — | — | |
| SCHEMBL1415115 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL4662825 | 0.79 | TSHR (0.63) | — | |
| SCHEMBL56403 | 0.79 | TSHR (0.63) | — | |
| SCHEMBL467980 | 0.79 | TRPA1 (0.52) | — | |
| SCHEMBL57069 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL467981 | 0.79 | TRPA1 (0.52) | — | |
| SCHEMBL467930 | 0.79 | TRPA1 (0.52) | — | |
| SCHEMBL16264827 | 0.78 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010814-A | (2S, 4R) -1-Fmoc-4- (O-allyloxycarbonyl methyl) -proline and synthesis method thereof | 杭州澳赛诺医药技术有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-113195450-B | Synthesis of substituted heterocycle fused gamma-carbolines | 细胞内治疗公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116947776-A | Hydroxy chalcone carboxyl derivative, preparation method and application thereof | 北京秦天科技集团有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116589440-A | Synthesis method of methyl esculetin sodium acetate | 峰成医药科技(天津)有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-20220064166-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA-CELLULAR THERAPIES, INC. | 2022-03-03 | — | — | US | claimed |
| CN-109810130-B | Rigid linear C60-fluoroboric fluorescent triplet-state photosensitized molecule and preparation method thereof | 合肥学院 | 2021-12-07 | — | — | CN | claimed |
| EP-3898581-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | Intra-Cellular Therapies, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-110627765-B | Preparation method of ticagrelor key intermediate | 浙江乐普药业股份有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-113195450-A | Synthesis of substituted heterocycle fused gamma-carbolines | 细胞内治疗公司 | 2021-07-30 | — | — | CN | claimed |
| CN-112480022-A | 3, 4-dichloroisothiazole-beta-keto acid ester derivatives, and preparation method and application thereof | 南开大学 | 2021-03-12 | — | — | CN | claimed |
| US-6657081-B1 | Extraction of actinides and lanthanides from aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2003-12-02 | — | — | US | claimed |
| EP-1133501-B1 | CALIXARENE DERIVATIVES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2003-02-12 | — | — | EP | claimed |
| US-5919933-A | PHOTOSTABILITY, OXIDATION RESISTANCE, RADIATION RESISTANCE, HEAT RESISTANCE | CLARIANT GMBH (DE) | 1999-07-06 | — | — | US | claimed |
| CN-1173493-A | Novel light stabilizers based on sterically hindered amines | HOECHST AG (DE) | 1998-02-18 | — | — | CN | claimed |
| US-4980485-A | Method of manufacturing optically-active periplanone-b | JAPAN TOBACCO INC. (JP) | 1990-12-25 | — | — | US | claimed |
| EP-0213506-B1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1989-02-15 | — | — | EP | claimed |
| WO-1988007537-A1 | NOVEL PROSTAGLANDIN INTERMEDIATES MODIFIED IN THE omega-CHAIN AND PROCESS FOR PREPARING SAME | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-10-06 | — | — | WO | claimed |
| EP-0220044-A2 | 4(4-oxo-1,4-dihydropyridin-1-yl)phenyl derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-04-29 | — | — | EP | claimed |
| EP-0213506-A1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1987-03-11 | — | — | EP | claimed |
| US-4487957-A | Process for the preparation of alkyl 4-methyl-3-formyl-penten-1-oates | ROUSSEL UCLAF (FR) | 1984-12-11 | — | — | US | claimed |