Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581710 | 1.00 | MOK (0.59) | MOKMAPTSMN1; SMN2NPY1RRECQL | |
| SCHEMBL19475271 | 0.76 | MOK (0.84) | MOKMAPTKDM4EALDH1A1GPR55 | |
| SCHEMBL19475531 | 0.74 | MOK (1.00) | MOKMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL30457868 | 0.73 | KDM4E (0.54) | MOKMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL29014005 | 0.73 | KDM4E (0.54) | MOKMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL19475310 | 0.70 | MOK (0.77) | MOKMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28609409 | 0.70 | MTOR (0.72) | PIK3CAMTORPIK3CG | |
| SCHEMBL14470414 | 0.68 | RAB9A (0.70) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL19667014 | 0.67 | GBA1 (0.57) | MAPTSMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL13253435 | 0.67 | NPSR1 (0.72) | MOKMAPTSMN1; SMN2NPY1RRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113082036-B | Dual inhibitor targeting JAK/STAT and NF kappa B signal pathways and application thereof | 中国海洋大学 | 2022-11-01 | — | — | CN | claimed |
| CN-113082036-B | Dual inhibitor targeting JAK/STAT and NF kappa B signal pathways and application thereof | 中国海洋大学 | 2022-11-01 | — | — | CN | disclosed |