Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.36 |
| ▸ | ESR1 | P03372 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31541237 | 0.84 | ESR2 (0.38) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL6797459 | 0.71 | DRD2 (0.43) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL630543 | 0.70 | ESR1 (0.40) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL4893807 | 0.69 | ESR2 (0.39) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL31280223 | 0.68 | ESR1 (0.41) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL6796118 | 0.67 | ESR1 (0.42) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL19484850 | 0.67 | ESR1 (0.40) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL12714150 | 0.67 | ESR2 (0.43) | ESR2ESR1 | |
| SCHEMBL6988847 | 0.65 | DRD2 (0.44) | ESR2ESR1DRD2DRD1DRD3 | |
| SCHEMBL29966509 | 0.65 | OPRK1 (0.44) | ESR2ESR1DRD2DRD1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206737-A1 | TETRAHYDRONAPHTHALENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-10-06 | — | — | WO | disclosed |