Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12526403 | 1.00 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL22557298 | 0.92 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL12494119 | 0.88 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL3936383 | 0.88 | CYP1A2 (0.43) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL9655999 | 0.84 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL12526399 | 0.83 | CYP2C19 (0.50) | GAACYP1A2MAPTALDH1A1CYP2C19 | |
| SCHEMBL19089740 | 0.83 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL10992041 | 0.81 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL9657467 | 0.81 | FFAR1 (0.50) | ADRA2AADRA2BADRA2CGAACYP1A2 | |
| SCHEMBL3928261 | 0.81 | MAPT (0.50) | GAACYP1A2MAPTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894469-A | Preparation method of 2- (3- (5-nitropyridine-2-yl) propyl) oxazole serving as intermediate of prochloraz | 江苏睿实生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115286623-B | Synthesis method of pramipexole and intermediate thereof | 深圳湾实验室 | 2024-09-10 | — | — | CN | disclosed |
| CN-113717166-B | Synthesis method of pramipexole | 杭州科巢生物科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115894469-A | Preparation method of 2- (3- (5-nitropyridine-2-yl) propyl) oxazole serving as intermediate of prochloraz | 江苏睿实生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894469-A | Preparation method of 2- (3- (5-nitropyridine-2-yl) propyl) oxazole serving as intermediate of prochloraz | 江苏睿实生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115286623-A | Process for synthesis of prochloraz and intermediate thereof | 深圳湾实验室 | 2022-11-04 | — | — | CN | disclosed |