Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxypethidine SCHEMBL25246 | 1.00 | OPRM1 (0.74) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Hydroxypethidine SCHEMBL317328 | 0.99 | OPRM1 (0.74) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL12369084 | 0.95 | OPRM1 (0.67) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Ketobemidone SCHEMBL28086319 | 0.91 | OPRM1 (0.72) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL4950745 | 0.89 | OPRM1 (0.57) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL5756148 | 0.86 | OPRM1 (0.72) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Meperidine SCHEMBL25431 | 0.85 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Meperidine SCHEMBL41046 | 0.84 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Meperidine SCHEMBL2860723 | 0.84 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| Meperidine SCHEMBL28905219 | 0.84 | OPRM1 (0.97) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295508-A | Opioid dosage reduction compositions and methods of use thereof | 迈索布拉斯特国际有限公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-1765303-B2 | ORAL TABLET SAFEGUARDED AGAINST ABUSE | GRUENENTHAL GMBH (DE) | 2022-11-23 | — | — | EP | disclosed |