Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NCK1 | P16333 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874626 | 1.00 | CYP1A2 (0.43) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL29966762 | 0.87 | DYRK1A (0.38) | CYP1A2ALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL29966934 | 0.79 | BACE1 (0.41) | CYP1A2ALDH1A1KDM4EHPGDBACE1 | |
| SCHEMBL9190130 | 0.79 | TYMS (0.40) | ALDH1A1KDM4ELMNAGAACYP2A6 | |
| SCHEMBL28874637 | 0.79 | BACE1 (0.41) | CYP1A2ALDH1A1KDM4EHPGDBACE1 | |
| SCHEMBL30894672 | 0.79 | NCF1 (0.45) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9197572 | 0.79 | CYP1A2 (0.41) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9125505 | 0.79 | NCF1 (0.45) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL4640459 | 0.76 | ALDH1A1 (0.44) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9196002 | 0.76 | BACE1 (0.45) | CYP1A2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260122-B | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260122-A | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | disclosed |