Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.50 |
| ▸ | GSK3B | P49841 | 10/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113125 | 1.00 | PTPN1 (0.50) | PTPN1GSK3BARMAPTALDH1A1 | |
| SCHEMBL28278468 | 0.85 | MAPT (0.51) | ARMAPTALDH1A1HPGDTSHR | |
| SCHEMBL10066834 | 0.85 | AR (0.40) | ARMAPTALDH1A1HPGDTSHR | |
| SCHEMBL11808909 | 0.81 | GSK3B (0.52) | PTPN1GSK3BAR | |
| SCHEMBL6519545 | 0.81 | HPGD (0.50) | ARMAPTALDH1A1HPGD | |
| SCHEMBL6738215 | 0.80 | GSK3B (0.50) | PTPN1GSK3B | |
| SCHEMBL17290737 | 0.80 | MEN1 (0.48) | ARMAPTALDH1A1HPGDTSHR | |
| SCHEMBL8402587 | 0.79 | LMNA (0.53) | ARMAPTALDH1A1TSHR | |
| SCHEMBL6112852 | 0.79 | AR (0.43) | ARMAPTALDH1A1HPGD | |
| SCHEMBL6721408 | 0.78 | MAPT (0.47) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440078-B1 | HETEROCYCLIC GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD (IN) | 2022-09-28 | — | — | EP | disclosed |