Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 5/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810733 | 1.00 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL29820187 | 0.89 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL1446528 | 0.89 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL29473526 | 0.84 | ALOX5 (0.57) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12223406 | 0.84 | ALOX5 (0.57) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7050380 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL30497792 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL30497791 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12880138 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL29512056 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260126-B | Chiral quaternary ammonium salt with (S) -binaphthyl, preparation method and application | 湖南城市学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-115260126-B | Chiral quaternary ammonium salt with (S) -binaphthyl, preparation method and application | 湖南城市学院 | 2024-01-30 | — | — | CN | disclosed |
| CN-115260126-A | Chiral quaternary ammonium salt with (S) -binaphthyl and preparation method and application thereof | 湖南城市学院 | 2022-11-01 | — | — | CN | disclosed |
| CN-115260126-A | Chiral quaternary ammonium salt with (S) -binaphthyl and preparation method and application thereof | 湖南城市学院 | 2022-11-01 | — | — | CN | disclosed |