SCHEMBL810733

SCHEMBL810733

COCOc1ccc2ccccc2c1-c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX5 P09917 1/20 0.42
DHFR P00374 2/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
HTR1B P28222 5/20 0.38
NISCH Q9Y2I1 1/20 0.38
GSK3B P49841 1/20 0.37
ADK P55263 1/20 0.37
DNMT1 P26358 1/20 0.37
SLC22A12 Q96S37 1/20 0.36
HTR1D P28221 1/20 0.36
CNR2 P34972 1/20 0.36
SLC6A4 P31645 1/20 0.36
HRH1 P35367 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29967345 1.00 MAPT (0.50) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29820187 0.89 MAPT (0.63) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL1446528 0.89 MAPT (0.63) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29473526 0.84 ALOX5 (0.57) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL12223406 0.84 ALOX5 (0.57) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL7050380 0.82 MAPT (0.39) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL30497792 0.82 MAPT (0.39) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL30497791 0.82 MAPT (0.39) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL12880138 0.82 MAPT (0.75) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29512056 0.82 MAPT (0.75) MAPTMEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184503-A Compound for identifying chiral amino alcohol, fluorescent probe, preparation method and application thereof 海南大学 2024-06-14 CN claimed
CN-117567286-A Fluorescent probe for specifically recognizing chiral threitol, preparation and application thereof 海南大学 2024-02-20 CN claimed
CN-115340458-B Compound for recognizing chiral arginine, fluorescent probe and preparation method thereof 海南大学 2023-05-26 CN claimed
CN-114956975-A Ammonia gas detection substance and device thereof 海南大学 2022-08-30 CN claimed
CN-114591209-A BINOL-based fluorescent probe, synthetic method thereof and application thereof in cadmium ion detection 兰州大学 2022-06-07 CN claimed
CN-113233966-B Chiral fluorescence sensor, preparation method thereof and application thereof in chiral amino acid recognition 中国药科大学 2022-03-08 CN claimed
CN-113233966-A Chiral fluorescence sensor, preparation method thereof and application thereof in chiral amino acid recognition 中国药科大学 2021-08-10 CN claimed
CN-118184503-A Compound for identifying chiral amino alcohol, fluorescent probe, preparation method and application thereof 海南大学 2024-06-14 CN disclosed
CN-117567286-A Fluorescent probe for specifically recognizing chiral threitol, preparation and application thereof 海南大学 2024-02-20 CN disclosed
US-11685810-B2 Process for polymerizing beta-butyrolactone Technische Universität München (DE) 2023-06-27 US disclosed
CN-114956975-B Ammonia detection substance and device thereof 海南大学 2023-05-09 CN disclosed
CN-113979975-B Chiral phosphoric acid catalyzed aryl allyl tertiary alcohol kinetic resolution method 浙江工业大学 2023-02-28 CN disclosed
CN-113620901-B Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2023-02-10 CN disclosed
US-7754899-B2 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-07-13 US disclosed
US-20100113835-A1 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-05-06 US disclosed
US-20100113815-A1 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-05-06 US disclosed
US-20100113835-A1 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-05-06 US disclosed
EP-1452537-B1 PROCESS FOR PREPARATION OF DIPHOSPHINE COMPOUNDS AND INTERMEDIATES FOR THE PROCESS TAKEDA PHARMACEUTICAL (JP) 2009-08-05 EP disclosed
US-20080081916-A1 Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-04-03 US disclosed
US-20080081916-A1 Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081916-A1 Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method INTS9, RAD54L, CD99 MAPT 3728/4885MEN1 983/4885KMT2A 2302/4885
US-11685810-B2 Process for polymerizing beta-butyrolactone CYP17A1, COASY, BBOX1 MAPT 1239/4885MEN1 1992/4885KMT2A 2970/4885
US-20100113815-A1 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method RAD54L, ATXN2L, CD99 MAPT 3282/4885MEN1 1185/4885KMT2A 1663/4885
US-20100113835-A1 Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method RAD54L, ATXN2L, CD99 MAPT 3282/4885MEN1 1185/4885KMT2A 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.