Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30733946 | 0.78 | PLAU (0.49) | ABCB1KDM4EHPGDPTPN1PLAU | |
| SCHEMBL7863078 | 0.71 | KDM4E (0.50) | KDM5AKDM4CKDM5BKDM2BKDM4E | |
| SCHEMBL11240930 | 0.68 | KDM4E (0.60) | AKT1AKT2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL17434280 | 0.68 | HDAC1 (0.44) | KMT2AMEN1 | |
| SCHEMBL1428462 | 0.67 | TDP1 (0.42) | AKT1AKT2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL973778 | 0.66 | TDP1 (0.45) | AKT1AKT2KDM4ESMN1; SMN2KMT2A | |
| Diphenylmethane SCHEMBL28928022 | 0.65 | FOLH1 (0.62) | LMNAKMT2ATSHR | |
| SCHEMBL28555999 | 0.65 | NPC1 (0.38) | AKT1AKT2KMT2AMEN1HTT | |
| SCHEMBL27925527 | 0.64 | KDM4C (0.62) | KDM5AKDM4CKDM5BKDM2BKDM4E | |
| SCHEMBL22587714 | 0.64 | NR1H4 (0.43) | AKT1AKT2KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188876-A1 | FUSED RING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | 浙江大学 | 2022-09-15 | — | — | WO | disclosed |