Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663365 | 0.82 | ALPG (0.48) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11759583 | 0.79 | KDM4E (0.64) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22059444 | 0.79 | KDM4E (0.64) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28679155 | 0.79 | SMN1; SMN2 (0.64) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18015436 | 0.79 | KDM4E (0.64) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11009983 | 0.79 | PTAFR (0.46) | ALPG | |
| SCHEMBL11269027 | 0.79 | ALPG (0.70) | KDM4EALDH1A1HSD17B10ATMHPGD | |
| Doqualast SCHEMBL124450 | 0.78 | KDM4E (0.63) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11245977 | 0.78 | AKR1B1 (0.71) | KDM4EGLAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2427657 | 0.76 | KDM4E (1.00) | KDM4EGLAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332802-A | 11-Oxo-11H-pyrido[2,1-b]quinazoline-2-carboxylic acid and salts thereof, antiallergic compositions containing it and methods of suppressing allergic reactions with it | BOEHRINGER INGELHEIM KG (DE) | 1982-06-01 | — | — | US | disclosed |