Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410408 | 1.00 | WNT3A (0.48) | WNT3AJAK2JAK1MAPTALDH1A1 | |
| SCHEMBL23410608 | 0.90 | JAK2 (0.47) | WNT3AJAK2JAK1MAPTALDH1A1 | |
| SCHEMBL25410990 | 0.90 | JAK2 (0.43) | WNT3AJAK2JAK1MAPTALDH1A1 | |
| SCHEMBL23410660 | 0.89 | ALDH1A1 (0.43) | WNT3AMAPTALDH1A1LMNAMAP4K4 | |
| SCHEMBL29967081 | 0.89 | ALDH1A1 (0.43) | WNT3AMAPTALDH1A1LMNAMAP4K4 | |
| SCHEMBL23410444 | 0.89 | PDE10A (0.44) | WNT3AJAK2JAK1MAPTALDH1A1 | |
| SCHEMBL23410855 | 0.88 | ALDH1A1 (0.44) | WNT3AMAPTALDH1A1LMNAMAP4K4 | |
| SCHEMBL23410314 | 0.88 | ALDH1A1 (0.48) | JAK2JAK1MAPTALDH1A1LMNA | |
| SCHEMBL29898983 | 0.88 | ALDH1A1 (0.48) | JAK2JAK1MAPTALDH1A1LMNA | |
| SCHEMBL23410794 | 0.88 | PTPN2 (0.43) | WNT3AMAPTALDH1A1LMNAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065110-A1 | NOVEL COMPOUNDS FOR TREATMENT OF DISEASES RELATED TO DUX4 EXPRESSION | Facio Intellectual Property B.V. (NL) | 2022-10-05 | — | — | EP | disclosed |