Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28272548 | 0.99 | SIGMAR1 (0.53) | SIGMAR1DRD2CHRM2CHRM3MEN1 | |
| SCHEMBL6132761 | 0.82 | OPRM1 (0.39) | SIGMAR1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL17767856 | 0.81 | SIGMAR1 (0.51) | SIGMAR1DRD2CHRM2KMT2AMAPT | |
| SCHEMBL13161928 | 0.79 | HCRTR1 (0.42) | SIGMAR1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL13768897 | 0.77 | SIGMAR1 (0.48) | SIGMAR1DRD2CHRM2MEN1KMT2A | |
| SCHEMBL17767869 | 0.76 | SIGMAR1 (0.53) | SIGMAR1DRD2CHRM2MEN1KMT2A | |
| SCHEMBL6132736 | 0.71 | GAA (0.44) | SIGMAR1ALDH1A1GAA | |
| SCHEMBL4115394 | 0.69 | SIGMAR1 (0.72) | SIGMAR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8109044 | 0.68 | SIGMAR1 (0.70) | SIGMAR1CHRM2CHRM3MEN1KMT2A | |
| SCHEMBL6946078 | 0.68 | SIGMAR1 (0.70) | SIGMAR1CHRM2CHRM3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |