SCHEMBL29967989

SCHEMBL29967989

Clc1ccc2ccc3ccc(Cl)cc3c2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.52
CHEK1 O14757 1/20 0.48
TP53 P04637 1/20 0.45
AHR P35869 2/20 0.44
CMA1 P23946 1/20 0.44
LMNA P02545 1/20 0.44
TYMS P04818 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
HSD17B10 Q99714 1/20 0.41
DYRK1A Q13627 2/20 0.41
NR4A2 P43354 1/20 0.41
NOS1 P29475 1/20 0.41
F7 P08709 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5411000 1.00 CYP2A6 (0.52) CYP2A6CHEK1TP53AHRCMA1
SCHEMBL2406653 0.94 CYP2A6 (0.48) CYP2A6CHEK1TP53AHRCMA1
SCHEMBL1758306 0.87 ALDH1A1 (0.64) CYP2A6AHRLMNAALDH1A1CYP3A4
SCHEMBL26853391 0.87 CYP2A6 (0.48) CYP2A6CHEK1TP53AHRCMA1
SCHEMBL1758210 0.84 DHODH (0.43) CYP2A6CHEK1LMNAALDH1A1CYP3A4
SCHEMBL380109 0.83 HPRT1 (0.64) CYP2A6AHRLMNAALDH1A1CYP3A4
SCHEMBL23625556 0.81 ENPP2 (0.56) CYP2A6CHEK1
Hydrochloric Acid SCHEMBL8104845 0.81 HPRT1 (0.61) CYP2A6AHRLMNAALDH1A1CYP3A4
SCHEMBL15857708 0.81 DHODH (0.41) CYP2A6CHEK1LMNAALDH1A1
SCHEMBL4298982 0.79 CHUK (0.49) DYRK1ANR4A2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117099507-A Material for organic electroluminescent device 默克专利有限公司 2023-11-21 CN disclosed
CN-117084000-A Material for organic electroluminescent device 默克专利有限公司 2023-11-17 CN disclosed
CN-115280539-A Material for organic electroluminescent device 默克专利有限公司 2022-11-01 CN disclosed