Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 5/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763325 | 1.00 | EIF2AK4 (0.41) | EIF2AK4HDAC1HDAC6ABL1NPY5R | |
| SCHEMBL29969336 | 0.95 | NPY5R (0.37) | EIF2AK4HDAC1HDAC6ABL1NPY5R | |
| SCHEMBL23763007 | 0.95 | NPY5R (0.37) | EIF2AK4HDAC1HDAC6ABL1NPY5R | |
| Hydrochloric Acid SCHEMBL29967952 | 0.95 | NPY5R (0.37) | EIF2AK4HDAC1HDAC6ABL1NPY5R | |
| SCHEMBL29967990 | 0.92 | ALDH1A1 (0.42) | ABL1ROCK1CDC42BPBROCK2CDC42BPA | |
| SCHEMBL23763037 | 0.92 | ALDH1A1 (0.42) | ABL1ROCK1CDC42BPBROCK2CDC42BPA | |
| Hydrochloric Acid SCHEMBL29968440 | 0.91 | ALDH1A1 (0.41) | ABL1ROCK1CDC42BPBROCK2CDC42BPA | |
| SCHEMBL23763045 | 0.91 | MAPKAPK2 (0.38) | HDAC1HDAC6ABL1NPY5RROCK1 | |
| SCHEMBL29968473 | 0.91 | MAPKAPK2 (0.38) | HDAC1HDAC6ABL1NPY5RROCK1 | |
| SCHEMBL23763059 | 0.91 | NPY5R (0.38) | HDAC1HDAC6ABL1NPY5RGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |