Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563917 | 1.00 | PNMT (0.62) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL10249345 | 1.00 | PNMT (0.62) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL12136140 | 1.00 | PNMT (0.62) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| Hydrochloric Acid SCHEMBL30559539 | 0.98 | PNMT (0.60) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL7694750 | 0.87 | TAAR1 (0.55) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL24152546 | 0.86 | TAAR1 (0.73) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL13387614 | 0.86 | TAAR1 (0.73) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL4693239 | 0.86 | TAAR1 (0.50) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL598282 | 0.84 | TAAR1 (0.52) | PNMTTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL3126846 | 0.84 | TAAR1 (0.48) | PNMTTAAR1SLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444283-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | Tactogen Inc. (US) | 2024-10-16 | — | — | EP | claimed |
| WO-2023107715-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-06-15 | — | — | WO | claimed |
| EP-4444283-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | Tactogen Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107715-A1 | SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |