Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 7/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CDKL3 | Q8IVW4 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871255 | 1.00 | MAPK10 (0.54) | MAPK10TDO2ABL1BCRSETD7 | |
| SCHEMBL29968183 | 0.90 | NR1H4 (0.53) | MAPK10TDO2ABL1BCRSETD7 | |
| SCHEMBL28957360 | 0.90 | NR1H4 (0.53) | MAPK10TDO2ABL1BCRSETD7 | |
| SCHEMBL28871315 | 0.89 | MAPK1 (0.48) | MAPK10TDO2MAPK8MRGPRX4KIT | |
| SCHEMBL28871284 | 0.83 | MRGPRX4 (0.46) | MAPK10TDO2MAPK8MRGPRX4KIT | |
| SCHEMBL29967985 | 0.82 | NR1H4 (0.45) | TDO2ABL1BCRMRGPRX4KIT | |
| SCHEMBL29967878 | 0.82 | MAPK10 (0.45) | MAPK10TDO2MAPK8KITFLT3 | |
| SCHEMBL28871266 | 0.82 | NR1H4 (0.45) | TDO2ABL1BCRMRGPRX4KIT | |
| SCHEMBL28871262 | 0.82 | MAPK10 (0.45) | MAPK10TDO2MAPK8KITFLT3 | |
| SCHEMBL28871293 | 0.81 | PRKAB2 (0.45) | MAPK10TDO2MAPK8MRGPRX4KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |