Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763099 | 1.00 | PIM1 (0.38) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| Hydrochloric Acid SCHEMBL29968224 | 0.99 | PIM1 (0.38) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| SCHEMBL29968473 | 0.95 | MAPKAPK2 (0.38) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| SCHEMBL23763045 | 0.95 | MAPKAPK2 (0.38) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| SCHEMBL29968477 | 0.95 | PIM1 (0.42) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| SCHEMBL23763376 | 0.95 | PIM1 (0.42) | PIM1NPY5RMAPKAPK2ABL1KIT | |
| SCHEMBL23763007 | 0.91 | NPY5R (0.37) | PIM1NPY5RABL1KIT | |
| SCHEMBL29969336 | 0.91 | NPY5R (0.37) | PIM1NPY5RABL1KIT | |
| SCHEMBL23763037 | 0.90 | ALDH1A1 (0.42) | PIM1MAPKAPK2ABL1 | |
| SCHEMBL29967990 | 0.90 | ALDH1A1 (0.42) | PIM1MAPKAPK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |