Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22440169 | 0.82 | ALDH1A1 (0.32) | TSHRALDH1A1MAPK1 | |
| SCHEMBL6244589 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL28522397 | 0.78 | CYP2D6 (0.32) | TSHRCYP2D6CYP2C19HIF1AGRM2 | |
| SCHEMBL9154532 | 0.78 | ALDH1A1 (0.32) | ALDH1A1GRM2GRM3 | |
| SCHEMBL7540204 | 0.77 | ALDH1A1 (0.37) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL18302657 | 0.77 | ALDH1A1 (0.37) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL5718550 | 0.75 | ALDH1A1 (0.43) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL5249504 | 0.75 | TET2 (0.38) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL6519062 | 0.74 | ALDH1A1 (0.38) | TSHRALDH1A1MAPK1 | |
| SCHEMBL3193100 | 0.73 | ALDH1A1 (0.34) | TSHRHIF1AALDH1A1MAPK1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030050426-A1 | Synthesized through ring-opening polymerization of functionalized epoxides alone or in combination with cyclic esters under mild, controlled conditions | SHASTRI VENKATRAM P (US) | 2003-03-13 | — | — | US | claimed |
| WO-2003000766-A1 | FUNCTIONALIZED DEGRADABLE POLYMERS | SHASTRI VENKATRAM PRASAD (US) | 2003-01-03 | — | — | WO | claimed |
| US-7658998-B2 | Mixture of biocompatibility polymer and active materials, drugs | ALKERMES CONTROLLED THERAPEUTICS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20040247870-A1 | Method of preparing sustained release microparticles | ALKERMES, INC. | 2004-12-09 | — | — | US | disclosed |
| WO-2004064752-A2 | METHOD OF PREPARING SUSTAINED RELEASE MICROPARTICLES | ALKERMES CONTROLLED THERAPEUTICS, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
| US-6730772-B2 | SYNTHESIZED THROUGH RING-OPENING POLYMERIZATION OF FUNCTIONALIZED EPOXIDES ALONE OR IN COMBINATION WITH CYCLIC ESTERS UNDER MILD, CONTROLLED CONDITIONS | SHASTRI VENKATRAM P (US) | 2004-05-04 | — | — | US | disclosed |
| US-20030050426-A1 | Synthesized through ring-opening polymerization of functionalized epoxides alone or in combination with cyclic esters under mild, controlled conditions | SHASTRI VENKATRAM P (US) | 2003-03-13 | — | — | US | disclosed |
| WO-2003000766-A1 | FUNCTIONALIZED DEGRADABLE POLYMERS | SHASTRI VENKATRAM PRASAD (US) | 2003-01-03 | — | — | WO | disclosed |