Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540204 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPK1CYP2D6CYP2C19 | |
| SCHEMBL18302657 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPK1CYP2D6CYP2C19 | |
| SCHEMBL10340048 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL8751000 | 0.77 | ACLY (0.32) | ALDH1A1 | |
| SCHEMBL3193100 | 0.77 | ALDH1A1 (0.34) | ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL2996873 | 0.75 | TSHR (0.37) | ALDH1A1TSHRMAPK1CYP2D6CYP2C19 | |
| SCHEMBL21803027 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL16369954 | 0.75 | THRA (0.44) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL14836310 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16370142 | 0.75 | THRA (0.44) | TET2ALDH1A1TSHRHMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527064-B1 | PREPARATION OF LACTIC ACID DERIVATIVES AND THEIR USE | AROMAGEN CORP (US) | 2007-09-12 | — | — | EP | claimed |