Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.40 |
| ▸ | S100A9 | P06702 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21512963 | 1.00 | CCR4 (0.41) | CCR4CACNA1BCACNA1HS100A9MEN1 | |
| SCHEMBL21513773 | 0.88 | CACNA1B (0.41) | CCR4CACNA1BCACNA1HMEN1KMT2A | |
| SCHEMBL29969100 | 0.88 | CACNA1B (0.41) | CCR4CACNA1BCACNA1HMEN1KMT2A | |
| SCHEMBL29969263 | 0.88 | CACNA1B (0.48) | CACNA1BCACNA1HHTTALDH1A1LMNA | |
| SCHEMBL21513746 | 0.88 | CACNA1B (0.48) | CACNA1BCACNA1HHTTALDH1A1LMNA | |
| SCHEMBL21513455 | 0.87 | LMNA (0.48) | CACNA1BCACNA1HMEN1KMT2AHTT | |
| SCHEMBL29969861 | 0.87 | LMNA (0.48) | CACNA1BCACNA1HMEN1KMT2AHTT | |
| SCHEMBL21512959 | 0.86 | CACNA1B (0.45) | CACNA1BCACNA1HS100A9HTTALDH1A1 | |
| SCHEMBL21513762 | 0.85 | ALDH1A1 (0.48) | CCR4CACNA1BCACNA1HMEN1KMT2A | |
| SCHEMBL29968192 | 0.85 | ALDH1A1 (0.48) | CCR4CACNA1BCACNA1HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187742-B2 | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | XRAD THERAPEUTICS, INC. (US) | 2025-01-07 | — | — | US | disclosed |
| US-20220315606-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD HOLDING CAYMAN LIMITED (KY) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315606-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | ATM, CHEK2, CHEK1 | CCR4 4246/4885CACNA1B 4878/4885CACNA1H 4862/4885 |
| US-12187742-B2 | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | ATM, CHEK2, CHEK1 | CCR4 4246/4885CACNA1B 4878/4885CACNA1H 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.