Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL27562486 | 1.00 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL27709113 | 1.00 | GPR84 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8366235 | 0.93 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL2382548 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL10396577 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL10937199 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL10943656 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL10942082 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL10939868 | 0.91 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL8957484 | 0.89 | AKR1B1 (0.70) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759780-B2 | Hindered amines | 3V SIGMA S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2020-07-30 | — | — | US | disclosed |
| EP-3424977-B1 | HINDERED POLYMERIC AMINES | 3V SIGMA SPA (IT) | 2020-03-18 | — | — | EP | disclosed |
| EP-3428156-B1 | HINDERED AMINES | 3V SIGMA SPA (IT) | 2020-02-12 | — | — | EP | disclosed |
| US-20190016702-A1 | HINDERED AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-17 | — | — | US | disclosed |
| EP-3428156-A1 | HINDERED AMINES | 3V SIGMA S.p.A (IT) | 2019-01-16 | — | — | EP | disclosed |
| EP-3424977-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.p.A (IT) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002631-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-03 | — | — | US | disclosed |
| US-9725578-B2 | Sterically hindered polymeric amines and their use as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2017-08-08 | — | — | US | disclosed |
| US-20170002178-A1 | STABILIZER MIXTURE | BASF SE (DE) | 2017-01-05 | — | — | US | disclosed |
| US-4863621-A | WEAR RESISTANCE, EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0317508-A2 | Aminic orthoester stabilized compositions | CIBA-GEIGY AG (CH) | 1989-05-24 | — | — | EP | disclosed |
| EP-0314623-A2 | Substituted hydroxylamine ester stabilizers | CIBA-GEIGY AG (CH) | 1989-05-03 | — | — | EP | disclosed |
| EP-0313517-A2 | Aliphatic esters of 1,3,2-oxazaphospholidines | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
| US-4803234-A | Piperidine compounds and their use as anti-oxidative, light or thermal induced degradation agents | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0299925-A1 | Piperidine-triazine compounds for use as stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| EP-0292437-A2 | Piperidylaminotriazine derivatives and their use as stabilizers | CIBA-GEIGY AG (CH) | 1988-11-23 | — | — | EP | disclosed |
| EP-0290388-A2 | Polyethylene stabilizer compositions comprising compounds with piperidine groups and metal compounds | CIBA-GEIGY AG (CH) | 1988-11-09 | — | — | EP | disclosed |
| EP-0290393-A2 | Piperidine compounds for use as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials | CIBA-GEIGY AG (CH) | 1988-11-09 | — | — | EP | disclosed |
| US-4517283-A | STABILIZED BY POLYALKYLPIPERIDINE COMPOUND AND PHENOL ANTIOXIDANT | CIBA-GEIGY AG (CH) | 1985-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | PARG, PARN, PUF60 | GPR84 1303/4885PPARG 4247/4885PPARD 2914/4885 |
| US-20190016702-A1 | HINDERED AMINES | PARG, TAAR5, PARN | GPR84 634/4885PPARG 2606/4885PPARD 2214/4885 |
| US-20170002178-A1 | STABILIZER MIXTURE | MRPL21, C9, C1R | GPR84 3778/4885PPARG 4473/4885PPARD 4327/4885 |
| US-10759780-B2 | Hindered amines | PARG, TAAR5, PARN | GPR84 634/4885PPARG 2606/4885PPARD 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.